gallium sulfate hydrate is moderately soluble in water and acid.
Easily dissipated from solids, gallium sulfate can be used for a wide range of applications that require compatible sulfates.
gallium sulfate is a stable and highly versatile compound that can be synthesized on silica gel to give a variety of compounds with different properties. For example, it can be used as a catalyst to produce n-heptyl p-hydroxybenzoate or as a strong acid cation ion exchange resin.
Galloid (Gallium) is a soft, silvery white metallic element that supercools quickly and has a low melting point, making it possible to work at very low temperatures without risking fire. It also combines well with non-metallic fillers such as diamond, graphite, and graphene to form pastes or putties.
The most important action of gallium is to affect iron homeostasis in malignant cells where it can act as a “mirror image” of iron. Inhibiting cellular iron uptake through transferrin receptor-mediated endocytosis of the metal is one mechanism by which gallium inhibits tumor growth, but other pathways are also involved.
These include inhibition of ribonucleotide reductase synthesis and the production of pro-apoptotic cytokines. In addition, gallium nitrate and a new gallium compound, gallium maltolate, activate an intrinsic pathway in lymphoma CCRF-CEM cells that induces apoptosis through the activation of proapoptotic Bax and loss of mitochondrial membrane potential and cytochrome c release from the mitochondrion [81].
These effects are independent of transferrin receptor-mediated uptake, which makes gallium a useful antineoplastic agent for a range of different cancers. In addition, the lack of cross-resistance to conventional chemotherapeutic drugs and antibiotics means that gallium-based therapies could be designed specifically for specific cancers, making it even more attractive for drug development.